GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs56322409 | 1 | rs11592213 | chr10:97396103 | ENTPD1 | chr10:97471536-97637022:+ | 0.19 | 4.94 | 1.15E-6 | Blood metabolite levels |
| BLCA | cis | rs2555155 | 1 | rs11604149 | chr11:6519642 | RRP8 | chr11:6621154-6624811:- | -0.21 | -3.87 | 0.000127 | DNA methylation (variation) |
| BLCA | cis | rs7927771 | 1 | rs11605774 | chr11:47832793 | C1QTNF4 | chr11:47611216-47615961:- | -0.3 | -5.58 | 4.54E-8 | Subjective well-being |
| BLCA | cis | rs116139393 | 1 | rs116139393 | chr7:6771660 | PMS2CL | chr7:6749757-6793492:+ | -0.45 | -6.41 | 4.4E-10 | Alzheimer's disease (APOE e4 interaction) |
| BLCA | cis | rs11622475 | 1 | rs11622475 | chr14:104509076 | TDRD9 | chr14:104394817-104519002:+ | 0.29 | 4.47 | 1.05E-5 | Bipolar disorder |
| BLCA | cis | rs11622475 | 1 | rs11625697 | chr14:104464800 | TDRD9 | chr14:104394817-104519002:+ | 0.33 | 5.37 | 1.37E-7 | Bipolar disorder |
| BLCA | cis | rs2239557 | 1 | rs11628710 | chr14:74649280 | LIN52 | chr14:74551656-74667117:+ | 0.37 | 8.44 | 6.55E-16 | Common traits (Other) |
| BLCA | cis | rs12908161 | 1 | rs11632465 | chr15:85282045 | LOC388152 | chr15:84867600-84898920:- | -0.24 | -4.17 | 3.84E-5 | Schizophrenia |
| BLCA | cis | rs12908161 | 1 | rs11637142 | chr15:85295927 | LOC388152 | chr15:84867600-84898920:- | -0.24 | -4.12 | 4.63E-5 | Schizophrenia |
| BLCA | cis | rs12908161 | 1 | rs11638290 | chr15:85227636 | LOC388152 | chr15:84867600-84898920:- | -0.25 | -4.27 | 2.47E-5 | Schizophrenia |
| BLCA | cis | rs950169 | 1 | rs11638297 | chr15:84782417 | LOC388152 | chr15:84867600-84898920:- | -0.27 | -4.73 | 3.09E-6 | Schizophrenia |
| BLCA | cis | rs950169 | 1 | rs11638394 | chr15:84778928 | LOC388152 | chr15:84867600-84898920:- | -0.27 | -4.67 | 4.27E-6 | Schizophrenia |
| BLCA | cis | rs11644601 | 1 | rs11644601 | chr16:15172118 | RRN3 | chr16:15153881-15188158:- | -0.25 | -3.91 | 0.000109 | Metabolite levels (lipid measures) |
| BLCA | cis | rs11645002 | 1 | rs11645002 | chr16:20617841 | ACSM1 | chr16:20634559-20709066:- | 0.38 | 5.45 | 9.01E-8 | Urinary metabolites |
| BLCA | cis | rs4494548 | 1 | rs11646919 | chr16:20400969 | C16orf88 | chr16:19717676-19729492:- | -0.35 | -3.85 | 0.000137 | Urinary uromodulin levels |